Shahid Beheshti
University of Medical Sciences

 

1 2 3
The Infertility and Reproductive Health Research Center (IRHRC) proudly announce its readiness to collaborate with Students , Doctors and Experts from non-faculty from various academic fields to convey their Research Ideas to national and international Professors from all over the globe and also administrative and executive activities for research projects.
Latest Headlines : 
Main Menu
Visitors` Statistics
 this page : 2684
 today : 41
 total : 20560
 online : 2
 time : 0.19
 


  Print        Send to Friend

Another finding by IRHRC research crew

Uterine and Serum Glycodelin Concentration in Recurrent Implantation Failure Versus Normal Fertile Women on Implantation Window

Uterine and Serum Glycodelin Concentration in Recurrent Implantation Failure Versus Normal Fertile Women on Implantation Window

Robabeh Taheripanah1 , Marzieh Zamaniyan2* , Shahrzad Akhoondzadeh1 , Anahita Taheripanah3 , Narges Malih4

 Abstract Objectives: Glycodelin is a factor which regulates immunological activity and is required in implantation window. The present study was conducted to compare glycodelin concentrations in blood and uterine flushing samples from women with in vitro fertilization (IVF) failure and fertile controls. Materials and Methods: This was a prospective clinical trial including 20 women with IVF failure and 19 fertile participants. Both groups initially filled a special questionnaire including their demographic profile and prior failed IVF attempts. Then samples of uterine flushing and blood samples were taken to measure glycodelin concentrations. Results: There were significant differences between mean glycodelin concentrations in the case and control groups, both in serum glycodelin (30.1±5.30 vs. 44.5±11.85 ng/mL, P<0.001), and uterine flushing glycodelin concentrations (310.0±67.51 vs. 498.3±119.01 ng/mL, P<0.001). The mean total glycodelin concentration in uterine flushing was higher than serum in both groups (399.4±133.95 vs. 36.9±1.52 ng/mL, P<0.001). Conclusion: We found a significant decrease in glycodelin concentrations among patients with IVF failure. Since glycodelin has a role in immune system during endometrial receptivity, therefore, it may be required for prevention of IVF failures. Keywords: Embryo implantation, Endometrium, Fertilization in vitro, Glycodelin, Infertility.


13:55 - 2017/05/06    /    number : 45904    /    Show Count : 87







Search



This site
Whole the Web
Library
Search Engine
 

 

Infertility and Reproductive Health Research Center

Shahid Beheshti University of Medical Sciences

t

Address : Iran, Tehran , Tajrish Sq. , Shohada-e-Tajrish Hospital

Tel : +98 21 22 71 22 34
Fax : +98 21 22 72 42 15
Email:   " irhrc@sbmu.ac.ir "

 

        Quick Links

            

Affiliation :

Infertility and Reproductive Health Research Center , Shahid Beheshti University of Medical Sciences , Tehran, Iran

 
Copyright © 2012 Shahid Beheshti University of Medical Sciences... All rights reserved. | Privacy Policy